Product details

Nicotinamide adenine dinucleotide, commonly known as NAD+, is a coenzyme naturally present in living cells. It forms part of the NAD+/NADH redox pair, helping cells transfer energy and supporting numerous enzyme-controlled reactions. Its central role in cellular metabolism makes NAD+ an important reference material across a wide range of biochemical research.

Availability: In Stock
Product Name: NAD+ 500 mg
Format: Lyophilized Powder in Glass Vial
CAS Number: 53-84-9

Research information

Research Applications

NAD+ is studied in research involving:

Cellular energy and ATP production
Mitochondrial function
Oxidation-reduction reactions
Sirtuin enzyme activity
DNA repair and PARP signalling
Cellular stress and ageing-related pathways
Metabolic and circadian regulation

These areas concern NAD+ biology at the cellular and molecular level and do not establish therapeutic benefits.

Batch Documentation

Every batch is fully tracked to maintain complete product traceability. Following purchase, a Certificate of Analysis specific to the supplied batch will be sent to the email address used for the order. A supporting research-information PDF will also be provided to the same email address.

Disclaimer: Supplied strictly for laboratory research and analytical use only. Not for human or veterinary consumption.

Research-use requirements

For in vitro use only — intended for laboratory research and testing.
Not for human use — no administration in any form.
Must not be used in clinical trials involving humans.
Must not be sold to third parties for human investigational use.

Research product

NAD+

Name: NAD+
Price: 95.00 GBP
Availability: InStock

Product code: NLNAD500

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500mg1000mg

Format

Vial£55.00 · Lyophilised powderResearch Pen£67.00 · +£12.00 pen

Add 3ML Bacteriostatic Water 3mlCommonly used for reconstitution+£3.99

Quantity

3+: 5% off · 5+: 10% off

Same strength and format. Best product price applies; product offers do not combine.

£55.00

In Stock

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UK Royal Mail Tracked 24 delivery is £3.99, or free on orders over £100. Pay securely by bank or via WhatsApp once you place your order.

Product code: NLNAD500
Format: 500mg
Lot code: NLNAD500
Availability: In Stock
Test date: 21/05/2026
Documentation: Available on request

For laboratory research use only. Not for human consumption. Not intended to diagnose, treat, cure or prevent disease.

Explore the research

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Educational reading on mechanisms, scientific findings and evidence limitations.

Sample Preparation and Matrix Effects in Bioanalysis

Sample preparation aims to place the analyte in a form compatible with measurement while controlling contaminants and losses. Explore the experimental methods, interpretation limits and open questions that shape this field.

Analytical Method Validation: Accuracy, Precision and Specificity

Analytical validation demonstrates that a method is fit for its stated purpose. Explore the experimental methods, interpretation limits and open questions that shape this field.

Apoptosis: Understanding Programmed Cell Death

Apoptosis is a regulated cell-death programme that dismantles cells through protease cascades and coordinated membrane changes. Explore the experimental methods, interpretation limits and open questions that shape this field.

Autophagy and Cellular Recycling: What Researchers Measure

Autophagy delivers cytoplasmic material to lysosomes for degradation and recycling. Explore the experimental methods, interpretation limits and open questions that shape this field.

Cellular Senescence: Markers, Models and Interpretation

Cellular senescence is a durable stress-associated state that usually includes cell-cycle withdrawal and broader changes in metabolism, chromatin and secreted signals. Explore the experimental methods, interpretation limits and open questions that shape this field.

Circadian Clocks in Cell Biology

Circadian clocks generate approximately daily rhythms through interacting transcriptional and post-translational feedback loops. Explore the experimental methods, interpretation limits and open questions that shape this field.

Forced Degradation and Stability-Indicating Methods

Forced degradation deliberately exposes a material to stress so likely degradation pathways can be observed. Explore the experimental methods, interpretation limits and open questions that shape this field.

LC-MS Peptide Identification: Separating and Measuring Molecules

Liquid chromatography-mass spectrometry combines physical separation with mass-to-charge measurement. Explore the experimental methods, interpretation limits and open questions that shape this field.

Laboratory Data Integrity and ALCOA+ Principles

Data integrity means information remains complete, consistent and trustworthy throughout its lifecycle. Explore the experimental methods, interpretation limits and open questions that shape this field.

Limits of Detection and Quantification Explained

The limit of detection concerns whether a signal can be distinguished from background, while the limit of quantification concerns whether a value can be reported with acceptable performance. Explore the experimental methods, interpretation limits and open questions that shape this field.

Measurement Uncertainty: What a Laboratory Result Can Really Say

Measurement uncertainty expresses the range of values reasonably attributable to a measurand under stated conditions. Explore the experimental methods, interpretation limits and open questions that shape this field.

Metabolic Flexibility: How Cells Switch Between Fuels

Metabolic flexibility is the capacity to adjust fuel use when nutrient supply or energy demand changes. Explore the experimental methods, interpretation limits and open questions that shape this field.

Mitochondrial Biogenesis: Building and Measuring Cellular Capacity

Mitochondrial biogenesis expands or renews mitochondrial components through coordinated nuclear and mitochondrial gene expression, protein import, membrane synthesis and organelle dynamics. Explore the experimental methods, interpretation limits and open questions that shape this field.

Proteostasis and Protein Quality Control

Proteostasis is the network that balances protein synthesis, folding, trafficking and removal. Explore the experimental methods, interpretation limits and open questions that shape this field.

Reference Standards and Calibrators in Laboratory Analysis

Reference standards and calibrators connect an instrument response to an assigned identity or quantity. Explore the experimental methods, interpretation limits and open questions that shape this field.

Sirtuins in Metabolic Signalling and Cellular Stress

Sirtuins are NAD-dependent deacylase enzymes found in different cellular compartments. Explore the experimental methods, interpretation limits and open questions that shape this field.

The NAD+ Salvage Pathway: Recycling Nicotinamide in Cells

The NAD salvage pathway recycles nicotinamide into NAD. Explore the experimental methods, interpretation limits and open questions that shape this field.

The Unfolded Protein Response and Endoplasmic Reticulum Stress

The unfolded protein response monitors protein-folding conditions in the endoplasmic reticulum. Explore the experimental methods, interpretation limits and open questions that shape this field.

mTOR and Nutrient Sensing: Coordinating Growth and Energy

mTOR is a serine-threonine kinase operating in two major complexes. Explore the experimental methods, interpretation limits and open questions that shape this field.

NAD+ Research Grade: A Reagent Buying Checklist

Distinguish NAD+ from NADH and other related products. Check the supplied form, assay requirements and evidence before ordering research material.

5-Amino-1MQ: NNMT Inhibition and Metabolic Research

Explore 5-Amino-1MQ, NNMT inhibition, nicotinamide metabolism and preclinical findings, with clear limits on what animal studies establish.

Glutathione: Redox Biology, GPX4 and Human Research

Explore glutathione chemistry, oxidative-stress measurements, GPX4 research and differing human trial findings, with clear evidence boundaries.

MOTS-C: Mitochondrial Signalling, AMPK and Current Research

Understand MOTS-C, mitochondrial signalling, AMPK-related experiments and human exercise observations without confusing them with efficacy trials.

NAD+: Redox Chemistry, Cellular Compartments and Research Evidence

Explore NAD+ coenzyme biology, mitochondrial transport, sirtuin research and human metabolome findings, with clear limits on longevity claims.

Methylcobalamin Vitamin B12: Cofactor Biology and Research Evidence

Understand methylcobalamin, vitamin B12-dependent enzymes, one-carbon metabolism and why specific clinical findings cannot support broad energy claims.

AMPK and Cellular Energy Regulation: How Cells Respond to Demand

Explore AMPK’s energy-sensing role, upstream kinases, metabolic targets and the evidence needed to interpret claims of AMPK activation.

The Biology of Cellular Ageing: Mechanisms, Markers and Limits

Explore senescence, DNA maintenance, proteostasis and mitochondrial changes, while distinguishing ageing markers from demonstrated functional outcomes.

How to Read a Certificate of Analysis for Research Peptides

Read peptide COAs accurately: batch identity, HPLC area purity, mass spectrometry, content and the limits of what each analytical result establishes.

HPLC vs Mass Spectrometry: Complementary Tools for Peptide Testing

Compare chromatographic separation with mass analysis, understand LC-MS and recognise what matching peaks or molecular masses cannot prove.

Understanding Mitochondrial Function: Energy, Signals and Measurement

Explore mitochondrial respiration, ATP production, quality control and signalling, with a practical guide to interpreting mitochondrial research endpoints.

What Is NAD+? A Guide to Cellular Coenzymes and Redox Biology

Understand NAD+, NADH, redox reactions, salvage pathways and cellular compartments, with clear distinctions between coenzyme biology and product claims.

Understanding NNMT and Nicotinamide Metabolism

Explore how NNMT connects nicotinamide, methyl donors and cellular metabolism, and why enzyme inhibition claims require tissue-specific evidence.

The Science of Metabolic Regulation: Flux, Feedback and Organ Crosstalk

Understand metabolic flux, insulin signalling, nutrient sensing and organ interactions, and why one biomarker cannot describe whole-body metabolism.

What Does Peptide Purity Mean? Purity, Content and Activity Explained

Separate chromatographic purity, peptide content, identity and biological activity when interpreting research peptide analytical reports.

What Is Oxidative Stress? Redox Signals, Damage and Measurement

Understand reactive oxygen species, antioxidant systems and redox signalling, including why one fluorescent assay cannot establish oxidative damage.